Type 2 Diabetes and Bone

Se Min Kim; Lena Fan; Mishaela R. Rubin

doi:10.1007/978-3-030-84367-0_26

Type 2 Diabetes and Bone

Se Min Kim
, Lena Fan
, Mishaela R. Rubin

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

A 72-year-old Caucasian female with uncontrolled type 2 diabetes was evaluated for low bone density. The patient did not have diabetes-related micro- or macrovascular complications. There was no history of fracture. The initial work-up for other secondary osteoporosis was unremarkable. Diabetes-related bone disease poses a significant risk of fracture. However, it is under-recognized mainly because patients with diabetes often preserve bone density, which we use as a diagnostic and therapeutic yardstick in current practice. With the recent advancement in imaging techniques such as HR-pQCT and trabecular bone score (TBS), now we understand that patients with diabetes have impaired microskeletal structure, which accounts for the high risk of fracture. In this case, we discussed how to augment bone density using the FRAX tool and TBS to better categorize the risk of fracture in patients with type 2 diabetes. Also, we discussed currently available treatment options and issues to consider in treating patients with type 2 diabetes bone disease.

Original language	English
Title of host publication	A Case-Based Guide to Clinical Endocrinology, Third Edition
Publisher	Springer International Publishing
Pages	235-242
Number of pages	8
ISBN (Electronic)	9783030843670
ISBN (Print)	9783030843663
DOIs	https://doi.org/10.1007/978-3-030-84367-0_26
State	Published - 1 Jan 2022

Keywords

Diabetes-related bone disease
FRAX
Osteoporosis
TBS
Type 2 diabetes

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10.1007/978-3-030-84367-0_26

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title = "Type 2 Diabetes and Bone",

abstract = "A 72-year-old Caucasian female with uncontrolled type 2 diabetes was evaluated for low bone density. The patient did not have diabetes-related micro- or macrovascular complications. There was no history of fracture. The initial work-up for other secondary osteoporosis was unremarkable. Diabetes-related bone disease poses a significant risk of fracture. However, it is under-recognized mainly because patients with diabetes often preserve bone density, which we use as a diagnostic and therapeutic yardstick in current practice. With the recent advancement in imaging techniques such as HR-pQCT and trabecular bone score (TBS), now we understand that patients with diabetes have impaired microskeletal structure, which accounts for the high risk of fracture. In this case, we discussed how to augment bone density using the FRAX tool and TBS to better categorize the risk of fracture in patients with type 2 diabetes. Also, we discussed currently available treatment options and issues to consider in treating patients with type 2 diabetes bone disease.",

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AU - Fan, Lena

AU - Rubin, Mishaela R.

N1 - Publisher Copyright: © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2008, 2015, 2022

PY - 2022/1/1

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N2 - A 72-year-old Caucasian female with uncontrolled type 2 diabetes was evaluated for low bone density. The patient did not have diabetes-related micro- or macrovascular complications. There was no history of fracture. The initial work-up for other secondary osteoporosis was unremarkable. Diabetes-related bone disease poses a significant risk of fracture. However, it is under-recognized mainly because patients with diabetes often preserve bone density, which we use as a diagnostic and therapeutic yardstick in current practice. With the recent advancement in imaging techniques such as HR-pQCT and trabecular bone score (TBS), now we understand that patients with diabetes have impaired microskeletal structure, which accounts for the high risk of fracture. In this case, we discussed how to augment bone density using the FRAX tool and TBS to better categorize the risk of fracture in patients with type 2 diabetes. Also, we discussed currently available treatment options and issues to consider in treating patients with type 2 diabetes bone disease.

AB - A 72-year-old Caucasian female with uncontrolled type 2 diabetes was evaluated for low bone density. The patient did not have diabetes-related micro- or macrovascular complications. There was no history of fracture. The initial work-up for other secondary osteoporosis was unremarkable. Diabetes-related bone disease poses a significant risk of fracture. However, it is under-recognized mainly because patients with diabetes often preserve bone density, which we use as a diagnostic and therapeutic yardstick in current practice. With the recent advancement in imaging techniques such as HR-pQCT and trabecular bone score (TBS), now we understand that patients with diabetes have impaired microskeletal structure, which accounts for the high risk of fracture. In this case, we discussed how to augment bone density using the FRAX tool and TBS to better categorize the risk of fracture in patients with type 2 diabetes. Also, we discussed currently available treatment options and issues to consider in treating patients with type 2 diabetes bone disease.

KW - Diabetes-related bone disease

KW - FRAX

KW - Osteoporosis

KW - TBS

KW - Type 2 diabetes

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EP - 242

BT - A Case-Based Guide to Clinical Endocrinology, Third Edition

PB - Springer International Publishing

ER -

Type 2 Diabetes and Bone

Abstract

Keywords

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