Type 1 Narcolepsy in Pregnancy: A Case Report and Review of Literature

Asnat Yuabov, Alexandra Kilinsky, Dina El Kady

Research output: Contribution to journalArticlepeer-review


Background  Type 1 narcolepsy (with cataplexy) is a rare disorder affecting the central nervous system and is characterized by the inability to control sleep-wake cycles. There is a paucity of data regarding management during pregnancy. Case  This is a 23-year-old primigravida with narcolepsy and cataplexy, treated with methylphenidate in the third trimester, resulting in an improvement of episodes of cataplexy. A review of the literature reveals information regarding options for medical management and the mode of delivery for these women. Conclusion  Type 1 narcolepsy can be treated with medications after consideration of risks and benefits. For patients who are symptomatic at the time of birth, cesarean section may be the preferred mode of delivery in women with type 1 narcolepsy.

Original languageEnglish
Pages (from-to)E120-E123
JournalAJP Reports
Issue number2
StatePublished - 26 Apr 2024
Externally publishedYes


  • Ceserean Section
  • cataplexy
  • delivery
  • medications
  • obstetric
  • pregnancy
  • type 1 narcolepsy


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