Two Wrongs Make a Right: Deficits in Reversal Learning after Orbitofrontal Damage Are Improved by Amygdala Ablation

Mark G. Baxter; Philip G.F. Browning

doi:10.1016/j.neuron.2007.03.008

Two Wrongs Make a Right: Deficits in Reversal Learning after Orbitofrontal Damage Are Improved by Amygdala Ablation

Mark G. Baxter, Philip G.F. Browning

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

Impaired cognitive flexibility after orbitofrontal damage has informed theories of orbitofrontal function and prefrontal cortex function generally. In this issue of Neuron, Stalnaker et al. demonstrate that reversal learning deficits after orbitofrontal damage in rats are eliminated by additional lesions of the basolateral amygdala. The involvement of orbitofrontal cortex in cognitive flexibility is via its interaction with the amygdala, and perhaps other brain areas, rather than an intrinsic property of this cortical region.

Original language	English
Pages (from-to)	1-3
Number of pages	3
Journal	Neuron
Volume	54
Issue number	1
DOIs	https://doi.org/10.1016/j.neuron.2007.03.008
State	Published - 5 Apr 2007
Externally published	Yes

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10.1016/j.neuron.2007.03.008

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Two Wrongs Make a Right: Deficits in Reversal Learning after Orbitofrontal Damage Are Improved by Amygdala Ablation

Abstract

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