Turkey versus guinea pig red blood cells: Hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1

Inna G. Ovsyannikova; Sarah J. White; Randy A. Albrecht; Adolfo García-Sastre; Gregory A. Poland

doi:10.1089/vim.2013.0111

Turkey versus guinea pig red blood cells: Hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1

Inna G. Ovsyannikova, Sarah J. White, Randy A. Albrecht, Adolfo García-Sastre, Gregory A. Poland

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

For influenza hemagglutination inhibition (HAI) assays, species selection of red blood cells (RBCs) is critical to determine antibody titers to influenza viruses reliably. We compared pandemic influenza virus A/H1N1 (pdH1N1) HAI titers using turkey or guinea pig RBCs. Turkey RBCs appear to be the more appropriate species choice for influenza A/pH1N1 HAI assays.

Original language	English
Pages (from-to)	174-178
Number of pages	5
Journal	Viral Immunology
Volume	27
Issue number	4
DOIs	https://doi.org/10.1089/vim.2013.0111
State	Published - 1 May 2014

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abstract = "For influenza hemagglutination inhibition (HAI) assays, species selection of red blood cells (RBCs) is critical to determine antibody titers to influenza viruses reliably. We compared pandemic influenza virus A/H1N1 (pdH1N1) HAI titers using turkey or guinea pig RBCs. Turkey RBCs appear to be the more appropriate species choice for influenza A/pH1N1 HAI assays.",

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AU - Poland, Gregory A.

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AB - For influenza hemagglutination inhibition (HAI) assays, species selection of red blood cells (RBCs) is critical to determine antibody titers to influenza viruses reliably. We compared pandemic influenza virus A/H1N1 (pdH1N1) HAI titers using turkey or guinea pig RBCs. Turkey RBCs appear to be the more appropriate species choice for influenza A/pH1N1 HAI assays.

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Turkey versus guinea pig red blood cells: Hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1

Abstract

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