Trends in prostate cancer incidence among Black men in the Caribbean and the United States

Charnita Zeigler-Johnson, Alicia C. McDonald, Paulo Pinheiro, Shannon Lynch, Emanuela Taioli, Shivam Joshi, Naomi Alpert, Jacqueline Baudin, Clarisse Joachim, Jacqueline Deloumeaux, Jo Ann Oliver, Bernard Bhakkan-Mambir, Murielle Beaubrun-Renard, Angel G. Ortiz, Camille Ragin

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: Prostate cancer incidence is highest for Black men of the African diaspora in the United States and Caribbean. Recent changes in recommendations for prostate cancer screening have been shown to decrease overall prostate cancer incidence and increase the likelihood of late stage disease. However, it is unclear how trends in prostate cancer characteristics among high risk Black men differ by geographic region during the changes in screening recommendations. Methods: In this study, we used population-based prostate cancer registry data to describe age-adjusted prostate cancer incidence trends from 2008 to 2015 among Black men from six geographic regions. We obtained data on incident Black prostate cancer patients from six cancer registries (in the United States: Florida, Alabama, Pennsylvania, and New York; and in the Caribbean: Guadeloupe and Martinique). After age standardization, we used descriptive analyses to compare the demographics and tumor characteristics by cancer registry site. The Joinpoint regression program was used to compare the trends in incidence by site. Results: A total of 59,246 men were analyzed. We found the highest incidence rates (per 100,000) for prostate cancer in the Caribbean countries (181.99 in Martinique and 176.62 in Guadeloupe) and New York state (178.74). Incidence trends decreased significantly over time at all sites except Martinique, which also showed significantly increasing rates of late stage (III/IV) and Gleason score 7+ tumors. Conclusions: We observed significant differences in prostate cancer incidence trends among Black men after major changes prostate screening recommendations. Future studies will examine the factors that differentially influence prostate cancer trends among the African diaspora.

Original languageEnglish
Pages (from-to)1207-1216
Number of pages10
JournalProstate
Volume83
Issue number12
DOIs
StatePublished - Sep 2023
Externally publishedYes

Keywords

  • Black men
  • Caribbean
  • incidence rates
  • prostate cancer

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