Treatment patterns and overall survival among patients with unresectable, stage III non-small-cell lung cancer

Priyanka Bobbili, Kellie Ryan, Mei S. Duh, Akanksha Dua, Ancilla W. Fernandes, Melissa Pavilack, Jorge E. Gomez

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Aim: To analyze treatment patterns and overall survival (OS) across time (2009-2014) among patients with unresected, stage III non-small-cell lung cancer (NSCLC). Patients & methods: Stage III NSCLC patients aged ≥65 years who initiated therapy were identified using SEER-Medicare data. Results: Among 4564 patients, 84% received chemotherapy (with or without radiotherapy), and 59% received chemoradiotherapy (CRT). Carboplatin + paclitaxel was the most frequent regimen. Median (interquartile range) OS among chemotherapy patients was 13.2 (6.0-28.9) months, and 14.8 (6.7-33.4) months among CRT patients. Among CRT patients, there was no difference in OS across years of CRT initiation. Conclusion: OS remained static across 2009-2014, indicating stagnancy in clinical outcomes for stage III NSCLC patients and a need for more effective therapeutic options.

Original languageEnglish
Pages (from-to)3381-3393
Number of pages13
JournalFuture Oncology
Volume15
Issue number29
DOIs
StatePublished - 2019

Keywords

  • chemoradiotherapy
  • chemotherapy
  • medicare
  • multi-modality SEER-medicare
  • standard-of-care

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