@article{7c7ea8db698541f8a88002551b95a602,
title = "Treatment of spine metastases in cancer: a review",
abstract = "As a consequence of the improvements in diagnostic technology along with gains in life expectancy of cancer patients, the incidence of spine metastases has increased. Spine metastases can affect the patient{\textquoteright}s quality of life and negatively impact on their prognosis. Multidisciplinary treatments involve surgery, chemotherapy, radiosurgery and radiotherapy. Spine metastases should be treated using a multidisciplinary and integrated approach that involves spinal surgeons, medical oncologists and radiologists. More research is required to elucidate the pathological mechanisms involved in the aetiology of spine metastasis. This review describes the current situation regarding the diagnosis of spine metastasis, what is understood about the pathological development of spine metastasis and the evolution of the multidisciplinary treatments that are available for patients with spine metastases.",
keywords = "Spine metastases, cancer, diagnosis, mechanisms, treatments",
author = "Yu Chen and Yayi He and Chao Zhao and Xuefei Li and Caicun Zhou and Hirsch, {Fred R.}",
note = "Funding Information: This study was supported in part by grants from the following organizations: National Natural Science Foundation of China (no. 81802255), Shanghai Pujiang Programme (no. 17PJD036), Shanghai Municipal Commission of Health and Family Planning Programme (no. 20174Y0131), National Key Research & Development Project (no. 2016YFC0902300), Major Disease Clinical Skills Enhancement Programme of three year action plan for promoting clinical skills and clinical innovation in municipal hospitals, Shanghai Shen Kang Hospital Development Centre Clinical Research Plan of SHDC (no. 16CR1001A), {\textquoteleft}Dream Tutor Outstanding Young Talents Programme{\textquoteright} (no. fkyq1901), Key Disciplines of Shanghai Pulmonary Hospital (no. 2017ZZ02012) and Shanghai Science and Technology Commission (no. 16JC1405900) Leading Talents in 2014. Publisher Copyright: {\textcopyright} The Author(s) 2019.",
year = "2019",
doi = "10.1177/0300060519888107",
language = "English",
volume = "48",
journal = "Journal of International Medical Research",
issn = "0300-0605",
publisher = "SAGE Publications Inc.",
number = "4",
}