Treatment of metastatic Ewing's sarcoma with BCNU

Jaime Palma; Salman Gailani; Arnold Freeman; Lucius Sinks; James F. Holland

doi:10.1002/1097-0142(197210)30:4<909::AID-CNCR2820300408>3.0.CO;2-Y

Treatment of metastatic Ewing's sarcoma with BCNU

Jaime Palma, Salman Gailani, Arnold Freeman, Lucius Sinks, James F. Holland

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Twelve patients with metastatic Ewing's sarcoma, ranging in age from 4 to 26 years, were treated with 1‐3‐bis chloroethyl nitrosourea (BCNU). The tumor in five of the patients showed objective tumor shrinkage with BCNU. In one patient, there was complete disappearance of the tumor lasting 21/2 years. In four other patients, there was partial improvement (50% shrinkage) lasting 2, 3, 6, and 8 months. BCNU may be of value in an adjuvant chemotherapy program as part of the initial treatment in an attempt to eradicate subclinical micrometastasis and thus increase the cure rate.

Original language	English
Pages (from-to)	909-913
Number of pages	5
Journal	Cancer
Volume	30
Issue number	4
DOIs	https://doi.org/10.1002/1097-0142(197210)30:4<909::AID-CNCR2820300408>3.0.CO;2-Y
State	Published - Oct 1972
Externally published	Yes

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10.1002/1097-0142(197210)30:4<909::AID-CNCR2820300408>3.0.CO;2-Y

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title = "Treatment of metastatic Ewing's sarcoma with BCNU",

abstract = "Twelve patients with metastatic Ewing's sarcoma, ranging in age from 4 to 26 years, were treated with 1‐3‐bis chloroethyl nitrosourea (BCNU). The tumor in five of the patients showed objective tumor shrinkage with BCNU. In one patient, there was complete disappearance of the tumor lasting 21/2 years. In four other patients, there was partial improvement (50% shrinkage) lasting 2, 3, 6, and 8 months. BCNU may be of value in an adjuvant chemotherapy program as part of the initial treatment in an attempt to eradicate subclinical micrometastasis and thus increase the cure rate.",

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T1 - Treatment of metastatic Ewing's sarcoma with BCNU

AU - Palma, Jaime

AU - Gailani, Salman

AU - Freeman, Arnold

AU - Sinks, Lucius

AU - Holland, James F.

PY - 1972/10

Y1 - 1972/10

N2 - Twelve patients with metastatic Ewing's sarcoma, ranging in age from 4 to 26 years, were treated with 1‐3‐bis chloroethyl nitrosourea (BCNU). The tumor in five of the patients showed objective tumor shrinkage with BCNU. In one patient, there was complete disappearance of the tumor lasting 21/2 years. In four other patients, there was partial improvement (50% shrinkage) lasting 2, 3, 6, and 8 months. BCNU may be of value in an adjuvant chemotherapy program as part of the initial treatment in an attempt to eradicate subclinical micrometastasis and thus increase the cure rate.

AB - Twelve patients with metastatic Ewing's sarcoma, ranging in age from 4 to 26 years, were treated with 1‐3‐bis chloroethyl nitrosourea (BCNU). The tumor in five of the patients showed objective tumor shrinkage with BCNU. In one patient, there was complete disappearance of the tumor lasting 21/2 years. In four other patients, there was partial improvement (50% shrinkage) lasting 2, 3, 6, and 8 months. BCNU may be of value in an adjuvant chemotherapy program as part of the initial treatment in an attempt to eradicate subclinical micrometastasis and thus increase the cure rate.

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VL - 30

SP - 909

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JO - Cancer

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ER -

Treatment of metastatic Ewing's sarcoma with BCNU

Abstract

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