Treatment of hepatitis C in coinfected patients

David Del Bello, Fanny Ita-Nagy, Jonathan Hand, Douglas Dieterich

Research output: Contribution to journalReview articlepeer-review


HCV and liver disease have emerged as major causes of morbidity and mortality in HIV-positive patients. Treating HCV in patients with HIV has been challenging up until a few years ago due to poorer outcomes with interferon-based therapies in this population. The direct-acting antiviral (DAA) agents offer a new era in the treatment of HCV for all patients regardless of HIV status. This article reviews multiple aspects of the care of the coinfected patient with a focus on the modern DAA agents. HCV clinical treatment trials involving HIV-positive patients and antiretroviral therapy/DAA drug-drug interactions are reviewed in detail.

Original languageEnglish
Pages (from-to)1291-1305
Number of pages15
JournalFuture Virology
Issue number12
StatePublished - Dec 2015


  • HIV
  • coinfection
  • direct-acting antivirals
  • hepatitis C


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