Treatment of Eyes With Diabetic Macular Edema That Had a Suboptimal Response to Antivascular Endothelial Growth Factor Therapy: 2-mg Intravitreal Triamcinolone Acetonide vs 0.7-mg Dexamethasone Implant

Brandon Kuley, Philip P. Storey, Maitri Pancholy, Turner D. Wibbelsman, Anthony Obeid, Carl Regillo, Sunir Garg

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Purpose: This article compares 2-mg intravitreal triamcinolone (IVT) and 0.7-mg dexamethasone (DEX) implant for the treatment of diabetic macular edema in eyes that had a suboptimal response to antivascular endothelial growth factor therapy. Methods: A single-center, retrospective review was conducted of patients receiving either IVT between January 1, 2013, and January 1, 2018, or patients receiving DEX between October 1, 2015, and January 1, 2018. Visual acuity and central macular thickness (CMT) were recorded at visit of first injection and all subsequent visits. Results: Twenty-five eyes were included in the DEX group and 32 eyes were included in the IVT group. Change in vision from baseline was similar between DEX and IVT at 6-month follow-up (1.1 lines vs 2.3 lines, respectively; P =.24). Mean decrease in CMT from baseline was not different at 6-month follow-up (DEX: 120 µm vs IVT: 185 µm; P =.17). Conclusions: DEX and 2-mg IVT both achieved improvement in vision and CMT with no significant differences between treatment groups at 6-month follow-up.

Original languageEnglish
Pages (from-to)372-376
Number of pages5
JournalJournal of VitreoRetinal Diseases
Volume4
Issue number5
DOIs
StatePublished - 1 Sep 2020
Externally publishedYes

Keywords

  • dexamethasone
  • diabetic macular edema
  • intravitreal steroids
  • triamcinolone

Fingerprint

Dive into the research topics of 'Treatment of Eyes With Diabetic Macular Edema That Had a Suboptimal Response to Antivascular Endothelial Growth Factor Therapy: 2-mg Intravitreal Triamcinolone Acetonide vs 0.7-mg Dexamethasone Implant'. Together they form a unique fingerprint.

Cite this