Treatment of Eosinophilic Esophagitis: Diet or Medication?

Mirna Chehade, Seema S. Aceves

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Eosinophilic esophagitis (EoE) is an antigen-triggered chronic disease of increasing prevalence in children and adults. Untreated or therapy-resistant EoE leads to complications of esophageal food impactions and luminal narrowing. The past decade has seen a number of new clinical trials for EoE therapies including elimination diets, proton pump inhibitors, swallowed topical corticosteroids, and biologics. In this review, we comment on the current state of the art for dietary and pharmacologic management of EoE and the need for future clinical trials to help tailor therapies to individual patients with this chronic disease.

Original languageEnglish
Pages (from-to)3249-3256
Number of pages8
JournalJournal of Allergy and Clinical Immunology: In Practice
Volume9
Issue number9
DOIs
StatePublished - Sep 2021

Keywords

  • Biologic
  • Corticosteroid
  • Diet
  • Eosinophil
  • Esophagus
  • Fibrosis
  • Food antigen
  • Proton pump inhibitor
  • Remodeling

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