Treatment of deep second-degree burns on the abdomen, thighs, and genitalia: use of tilapia skin as a xenograft

Translated title of the contribution: Treatment of deep second-degree burns on the abdomen, thighs, and genitalia: use of tilapia skin as a xenograft

Edmar Maciel Lima Júnior, Manoel Odorico Moraes Filho, Bruno Almeida Costa, Alex Marques Do Nascimento Uchôa, Camila Barroso Martins, Maria Elisabete Amaral De Moraes, Marina Becker Sales Rocha, Francisco Vagnaldo Fechine

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Tilapia skin has a non-infectious microbiota and a morphological structure similar to human skin. Phase II clinical studies, not yet published, have shown promising results in their use for the treatment of burns. In the protocols of these studies, patients with lesions in areas of skin folds, such as genitals and inguinal regions, were excluded, as it was thought that the biomaterial would not adhere properly, resulting in a lower degree of healing. Case report of a female patient, 18 years old, without comorbidities, with deep second-degree burns in the abdomen, inguinal region, part of the genitalia and upper half of both thighs, involving 13.5% of the total body surface area. Tilapia skin was applied to the lesions leading to a complete re-epithelialization with 16 days of treatment. No side effects were observed. Tilapia skin, therefore, brings the promise of an innovative product, easy to apply, and highly available, which can become the first animal skin nationally studied and registered by the Agência Nacional de Vigilância Sanitária, for use in the treatment of burns. This case report contributes to reduce the limitations concerning the anatomical areas appropriate for the application of tilapia skin, since, even with the need for skin replacement, good results were obtained with application to the genitalia and inguinal region.

Translated title of the contributionTreatment of deep second-degree burns on the abdomen, thighs, and genitalia: use of tilapia skin as a xenograft
Original languageEnglish
Pages (from-to)243-248
Number of pages6
JournalRevista Brasileira de Cirurgia Plastica
Volume35
Issue number2
DOIs
StatePublished - 2020
Externally publishedYes

Keywords

  • Biocompatible materials
  • Biological dressings
  • Burns
  • Cichlids
  • Tilapia

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