Treatment of advanced endometrial adenocarcinoma with cis-dichlorodiammine platinum (II) after intensive prior therapy

Gunter Deppe; Carmel J. Cohen; Howard W. Bruckner

doi:10.1016/0090-8258(80)90062-1

Treatment of advanced endometrial adenocarcinoma with cis-dichlorodiammine platinum (II) after intensive prior therapy

Gunter Deppe, Carmel J. Cohen, Howard W. Bruckner

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

Four of thirteen patients with advanced endometrial adenocarcinoma had an objective response to treatment with cis-dichlorodiammine platinum (II) by high-dose infusion after failing prior intensive combination chemotherapy. The median duration of response was 4 months and there were no unusual toxic reactions. The previous therapy included adriamycin, cyclophosphamide, 5-fluorouracil with progestins, or melphalan, 5-fluorouracil, and progestins.

Original language	English
Pages (from-to)	51-54
Number of pages	4
Journal	Gynecologic Oncology
Volume	10
Issue number	1
DOIs	https://doi.org/10.1016/0090-8258(80)90062-1
State	Published - 1980

Keywords

5-FU
5-fluorouracil
ADR
BSO
CTX
MEL
PI
Prog
SAL
SPL
TAH
adriamycin
bilateral salpingo-oophorectomy
cytoxan (generic is cyclophosphamide)
melphalan
pelvic irradiation
progestins
selective aortic lymphadenectomy
selective pelvic lymphadenectomy
total abdominal hysterectomy

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10.1016/0090-8258(80)90062-1

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@article{a2abd583727c498386187c8714141aef,

title = "Treatment of advanced endometrial adenocarcinoma with cis-dichlorodiammine platinum (II) after intensive prior therapy",

abstract = "Four of thirteen patients with advanced endometrial adenocarcinoma had an objective response to treatment with cis-dichlorodiammine platinum (II) by high-dose infusion after failing prior intensive combination chemotherapy. The median duration of response was 4 months and there were no unusual toxic reactions. The previous therapy included adriamycin, cyclophosphamide, 5-fluorouracil with progestins, or melphalan, 5-fluorouracil, and progestins.",

keywords = "5-FU, 5-fluorouracil, ADR, BSO, CTX, MEL, PI, Prog, SAL, SPL, TAH, adriamycin, bilateral salpingo-oophorectomy, cytoxan (generic is cyclophosphamide), melphalan, pelvic irradiation, progestins, selective aortic lymphadenectomy, selective pelvic lymphadenectomy, total abdominal hysterectomy",

author = "Gunter Deppe and Cohen, {Carmel J.} and Bruckner, {Howard W.}",

note = "Funding Information: 1 Supported in part by Contract l-CM43703 from the National Institutes of Health, and by 5-POI-CA15936 Center Grant. 2 Address reprint requests to Gunter Deppe, M.D., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, 1176F ifth Avenue, Suite I, New York, N.Y. 10029.",

year = "1980",

doi = "10.1016/0090-8258(80)90062-1",

language = "English",

volume = "10",

pages = "51--54",

journal = "Gynecologic Oncology",

issn = "0090-8258",

publisher = "Academic Press Inc.",

number = "1",

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T1 - Treatment of advanced endometrial adenocarcinoma with cis-dichlorodiammine platinum (II) after intensive prior therapy

AU - Deppe, Gunter

AU - Cohen, Carmel J.

AU - Bruckner, Howard W.

N1 - Funding Information: 1 Supported in part by Contract l-CM43703 from the National Institutes of Health, and by 5-POI-CA15936 Center Grant. 2 Address reprint requests to Gunter Deppe, M.D., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, 1176F ifth Avenue, Suite I, New York, N.Y. 10029.

PY - 1980

Y1 - 1980

N2 - Four of thirteen patients with advanced endometrial adenocarcinoma had an objective response to treatment with cis-dichlorodiammine platinum (II) by high-dose infusion after failing prior intensive combination chemotherapy. The median duration of response was 4 months and there were no unusual toxic reactions. The previous therapy included adriamycin, cyclophosphamide, 5-fluorouracil with progestins, or melphalan, 5-fluorouracil, and progestins.

AB - Four of thirteen patients with advanced endometrial adenocarcinoma had an objective response to treatment with cis-dichlorodiammine platinum (II) by high-dose infusion after failing prior intensive combination chemotherapy. The median duration of response was 4 months and there were no unusual toxic reactions. The previous therapy included adriamycin, cyclophosphamide, 5-fluorouracil with progestins, or melphalan, 5-fluorouracil, and progestins.

KW - 5-FU

KW - 5-fluorouracil

KW - ADR

KW - BSO

KW - CTX

KW - MEL

KW - PI

KW - Prog

KW - SAL

KW - SPL

KW - TAH

KW - adriamycin

KW - bilateral salpingo-oophorectomy

KW - cytoxan (generic is cyclophosphamide)

KW - melphalan

KW - pelvic irradiation

KW - progestins

KW - selective aortic lymphadenectomy

KW - selective pelvic lymphadenectomy

KW - total abdominal hysterectomy

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U2 - 10.1016/0090-8258(80)90062-1

DO - 10.1016/0090-8258(80)90062-1

M3 - Article

C2 - 7190531

AN - SCOPUS:0018869219

SN - 0090-8258

VL - 10

SP - 51

EP - 54

JO - Gynecologic Oncology

JF - Gynecologic Oncology

IS - 1

ER -

Treatment of advanced endometrial adenocarcinoma with cis-dichlorodiammine platinum (II) after intensive prior therapy

Abstract

Keywords

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