Treatment of a recurrent subdural hematoma using urokinase

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Previous reports describe the intraventricular, subarachnoid, and intraparenchymal use of thrombolytic agents. However, the use of thrombolytic agents in the management of extraaxial hematomas has not been described. Following the evacuation of a subacute subdural hematoma, this 48-yearold woman experienced declining neurologic function due to the reaccumulation of blood in the subdural space. Urokinase was administered via a subdural drain. The patient experienced rapid clinical improvement and radiographic resolution of the recrudescent subdural hematoma. If repeat surgical evacuation of a subdural hematoma is not possible, urokinase may be instilled into the subdural space to enhance drainage of a subdural hematoma.

Original languageEnglish
Pages (from-to)1235-1239
Number of pages5
JournalJournal of Neurotrauma
Issue number12
StatePublished - Dec 1999


  • Subdural hematoma
  • Thrombolysis
  • Urokinase


Dive into the research topics of 'Treatment of a recurrent subdural hematoma using urokinase'. Together they form a unique fingerprint.

Cite this