Traumatic neuromas of the penis: A clinical, histopathological and immunohistochemical study of 17 cases

Eduardo Salcedo, Anthony C. Soldano, Lesley Chen, Cameron K. Rokhsar, Sam T. Tam, Shane A. Meehan, Hideko Kamino

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

We present 17 penile traumatic neuromas. The mean patient age at presentation was 38 years (range 23-59 years). The most common site involved was the penile shaft. The lesions ranged from 1 to 7 mm in greatest dimension. The clinical diagnosis in all cases included condyloma acuminatum. In all cases, a history of trauma because of prior biopsy and/or circumcision was found. Histologically, all lesions showed similar features consisting of an increased number of dermal nerve bundles embedded within a fibrous stroma. Often, single or multiple Meissner corpuscle-like structures were noted in the papillary dermis. Our study suggests that circumcision or other forms of trauma to the skin of the penis likely plays an important role in the pathogenesis and clinical presentation of this peculiar neural neoplasm. We call attention to this entity because it is often clinically misdiagnosed as condyloma acuminatum.

Original languageEnglish
Pages (from-to)229-233
Number of pages5
JournalJournal of Cutaneous Pathology
Volume36
Issue number2
DOIs
StatePublished - Feb 2009
Externally publishedYes

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