Trastuzumab (Herceptin)-associated lung injury

Bobbak Vahid; Anita Mehrotra

doi:10.1111/j.1440-1843.2006.00907.x

Trastuzumab (Herceptin)-associated lung injury

Bobbak Vahid
, Anita Mehrotra

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

We report a case of trastuzumab pneumonitis in a patient with metastatic breast cancer. Bronchoalveolar lavage showed marked neutrophilia. A CT scan of the chest showed diffuse ground-glass opacities. The patient was treated with corticosteroids with a partial response. Trastuzumab-associated pneumonitis is not well described, and data in the literature is sparse. We describe the clinical and radiographical findings of trastuzumab-associated pneumonitis.

Original language	English
Pages (from-to)	655-658
Number of pages	4
Journal	Respirology
Volume	11
Issue number	5
DOIs	https://doi.org/10.1111/j.1440-1843.2006.00907.x
State	Published - Sep 2006
Externally published	Yes

Keywords

Drug-induced pneumonitis
Interstitial lung disease
Trastuzumab

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10.1111/j.1440-1843.2006.00907.x

Cite this

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title = "Trastuzumab (Herceptin)-associated lung injury",

abstract = "We report a case of trastuzumab pneumonitis in a patient with metastatic breast cancer. Bronchoalveolar lavage showed marked neutrophilia. A CT scan of the chest showed diffuse ground-glass opacities. The patient was treated with corticosteroids with a partial response. Trastuzumab-associated pneumonitis is not well described, and data in the literature is sparse. We describe the clinical and radiographical findings of trastuzumab-associated pneumonitis.",

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AU - Mehrotra, Anita

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AB - We report a case of trastuzumab pneumonitis in a patient with metastatic breast cancer. Bronchoalveolar lavage showed marked neutrophilia. A CT scan of the chest showed diffuse ground-glass opacities. The patient was treated with corticosteroids with a partial response. Trastuzumab-associated pneumonitis is not well described, and data in the literature is sparse. We describe the clinical and radiographical findings of trastuzumab-associated pneumonitis.

KW - Drug-induced pneumonitis

KW - Interstitial lung disease

KW - Trastuzumab

UR - https://www.scopus.com/pages/publications/33746877839

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EP - 658

JO - Respirology

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Trastuzumab (Herceptin)-associated lung injury

Abstract

Keywords

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