Liver transplantation is the treatment of choice for early hepatocellular carcinoma (HCC) as defined by the Milan criteria in the setting of cirrhosis and significant liver dysfunction, subject to donor organ availability; its role in patients with early, potentially resectable tumours and with tumours beyond the Milan criteria is controversial. Living donor liver transplantation and the advent of molecular indicators of prognosis promise to broaden and refine the application of transplantation for HCC.

Original languageEnglish
Title of host publicationClinical Dilemmas in Primary Liver Cancer
Number of pages8
ISBN (Electronic)9781119962205
ISBN (Print)9780470657973
StatePublished - 1 Jan 2011


  • Downstaging
  • Extended indications
  • Hepatocellular carcinoma
  • Liver resection
  • Liver transplantation
  • Living donor liver transplantation
  • Milan criteria
  • Molecular markers


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