Translational Research in Culture: AADAC, Diabetes, and Cardiovascular Disease

Ashish Misra; Edward A. Fisher

doi:10.1016/j.stem.2020.06.012

Translational Research in Culture: AADAC, Diabetes, and Cardiovascular Disease

Ashish Misra, Edward A. Fisher

Research output: Contribution to journal › Comment/debate

1 Scopus citations

Abstract

Many type 2 diabetes patients develop cardiovascular disease (CVD) while some are protected. Toyohara et al. (2020) find that elevated arylacetamide deacetylase (AADAC) expression in vascular smooth muscle cells (dVSMCs) differentiated from patient-derived induced pluripotent stem cells is associated with cardioprotection. AADAC overexpression alters multiple dVSMC properties and decreases murine CVD.

Original language	English
Pages (from-to)	6-7
Number of pages	2
Journal	Cell Stem Cell
Volume	27
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2020.06.012
State	Published - 2 Jul 2020
Externally published	Yes

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title = "Translational Research in Culture: AADAC, Diabetes, and Cardiovascular Disease",

abstract = "Many type 2 diabetes patients develop cardiovascular disease (CVD) while some are protected. Toyohara et al. (2020) find that elevated arylacetamide deacetylase (AADAC) expression in vascular smooth muscle cells (dVSMCs) differentiated from patient-derived induced pluripotent stem cells is associated with cardioprotection. AADAC overexpression alters multiple dVSMC properties and decreases murine CVD.",

author = "Ashish Misra and Fisher, {Edward A.}",

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AB - Many type 2 diabetes patients develop cardiovascular disease (CVD) while some are protected. Toyohara et al. (2020) find that elevated arylacetamide deacetylase (AADAC) expression in vascular smooth muscle cells (dVSMCs) differentiated from patient-derived induced pluripotent stem cells is associated with cardioprotection. AADAC overexpression alters multiple dVSMC properties and decreases murine CVD.

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Translational Research in Culture: AADAC, Diabetes, and Cardiovascular Disease

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