Translational regulation is an important aspect of gene regulation, particularly during early development of the fruit fly embryo when transcriptional mechanisms are untenable. Study of pattern formation and dosage compensation has identified several repressors that bind discrete sites in the untranslated portions of target mRNAs. These repressors do not work in isolation - each binds multiple sites in the appropriate mRNA, and the resulting RNA-protein complexes appear to recruit co-repressors by a variety of mechanisms.

Original languageEnglish
Pages (from-to)572-576
Number of pages5
JournalTrends in Genetics
Issue number11
StatePublished - 1 Nov 2002


Dive into the research topics of 'Translational repressors in Drosophila'. Together they form a unique fingerprint.

Cite this