Abstract
The objective of this study is to quantitate the real time electrical response of living cell membranes using high speed impedance techniques. Relaxation measurements are performed over the anticipated wide frequency (time) range of the kinetics of electrochemical surface processes for isolated cells under physiologically meaningful conditions. The results for the human red blood cell show the presence of three relaxation pathways. Using an electrochemical approach the specific model structure has been identified as containing a dielectric membrance capacitance, a first specific-adsorption like pathway and a second similar pathway. Preliminary data for the macrophage cell line show the existence of two relaxation pathways. Similar modeling results in the isolation of the dielectric membrane capacitance and also a specific adsorption-like pathway.
| Original language | English |
|---|---|
| Pages (from-to) | 658 |
| Number of pages | 1 |
| Journal | Electrochemical Society Extended Abstracts |
| Volume | 85-1 |
| State | Published - 1985 |