TY - JOUR
T1 - Transatlantic registries for minimally invasive liver surgery
T2 - towards harmonization
AU - van der Heijde, Nicky
AU - Görgec, Burak
AU - Beane, Joal D.
AU - Ratti, Francesca
AU - Belli, Giulio
AU - Benedetti Cacciaguerra, Andrea
AU - Calise, Fulvio
AU - Cillo, Umberto
AU - De Boer, Marieke T.
AU - Fagenson, Alexander M.
AU - Fretland, Åsmund A.
AU - Gleeson, Elizabeth M.
AU - de Graaff, Michelle R.
AU - Kok, Niels F.M.
AU - Lassen, Kristoffer
AU - van der Poel, Marcel J.
AU - Ruzzenente, Andrea
AU - Sutcliffe, Robert P.
AU - Edwin, Bjørn
AU - Aldrighetti, Luca
AU - Pitt, Henry A.
AU - Abu Hilal, Mohammad
AU - Besselink, Marc G.
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2023/5
Y1 - 2023/5
N2 - Background: Several registries focus on patients undergoing minimally invasive liver surgery (MILS). This study compared transatlantic registries focusing on the variables collected and differences in baseline characteristics, indications, and treatment in patients undergoing MILS. Furthermore, key variables were identified. Methods: The five registries for liver surgery from North America (ACS-NSQIP), Italy, Norway, the Netherlands, and Europe were compared. A set of key variables were established by consensus expert opinion and compared between the registries. Anonymized data of all MILS procedures were collected (January 2014–December 2019). To summarize differences for all patient characteristics, treatment, and outcome, the relative and absolute largest differences (RLD, ALD) between the smallest and largest outcome per variable among the registries are presented. Results: In total, 13,571 patients after MILS were included. Both 30- and 90-day mortality after MILS were below 1.1% in all registries. The largest differences in baseline characteristics were seen in ASA grade 3–4 (RLD 3.0, ALD 46.1%) and the presence of liver cirrhosis (RLD 6.4, ALD 21.2%). The largest difference in treatment was the use of neoadjuvant chemotherapy (RLD 4.3, ALD 20.6%). The number of variables collected per registry varied from 28 to 303. From the 46 key variables, 34 were missing in at least one of the registries. Conclusion: Despite considerable variation in baseline characteristics, indications, and treatment of patients undergoing MILS in the five transatlantic registries, overall mortality after MILS was consistently below 1.1%. The registries should be harmonized to facilitate future collaborative research on MILS for which the identified 46 key variables will be instrumental.
AB - Background: Several registries focus on patients undergoing minimally invasive liver surgery (MILS). This study compared transatlantic registries focusing on the variables collected and differences in baseline characteristics, indications, and treatment in patients undergoing MILS. Furthermore, key variables were identified. Methods: The five registries for liver surgery from North America (ACS-NSQIP), Italy, Norway, the Netherlands, and Europe were compared. A set of key variables were established by consensus expert opinion and compared between the registries. Anonymized data of all MILS procedures were collected (January 2014–December 2019). To summarize differences for all patient characteristics, treatment, and outcome, the relative and absolute largest differences (RLD, ALD) between the smallest and largest outcome per variable among the registries are presented. Results: In total, 13,571 patients after MILS were included. Both 30- and 90-day mortality after MILS were below 1.1% in all registries. The largest differences in baseline characteristics were seen in ASA grade 3–4 (RLD 3.0, ALD 46.1%) and the presence of liver cirrhosis (RLD 6.4, ALD 21.2%). The largest difference in treatment was the use of neoadjuvant chemotherapy (RLD 4.3, ALD 20.6%). The number of variables collected per registry varied from 28 to 303. From the 46 key variables, 34 were missing in at least one of the registries. Conclusion: Despite considerable variation in baseline characteristics, indications, and treatment of patients undergoing MILS in the five transatlantic registries, overall mortality after MILS was consistently below 1.1%. The registries should be harmonized to facilitate future collaborative research on MILS for which the identified 46 key variables will be instrumental.
KW - Laparoscopic liver surgery
KW - Liver surgery
KW - Minimally invasive liver surgery
KW - Nationwide registries
KW - Robotic liver surgery
UR - http://www.scopus.com/inward/record.url?scp=85145896075&partnerID=8YFLogxK
U2 - 10.1007/s00464-022-09765-y
DO - 10.1007/s00464-022-09765-y
M3 - Article
AN - SCOPUS:85145896075
SN - 0930-2794
VL - 37
SP - 3580
EP - 3592
JO - Surgical Endoscopy and Other Interventional Techniques
JF - Surgical Endoscopy and Other Interventional Techniques
IS - 5
ER -