Tracheal reconstruction with a pleuroperiosteal flap

Yosef P. Krespi, Hugh F. Biller, Se Min Baek

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Reconstruction of extensive tracheal defects remains a difficult surgical problem. In many experiments restoration of tracheal mucosa by autogenous or homologous soft tissue grafts has usually failed because of rejection or tracheal obstruction. This experimental work employed a two-stage surgical procedure that allowed reconstruction of extensive circumferential full-thickness defects of the trachea. Stage I involved the creation of a vascularized pleuroperiosteal flap that was formed into a rigid tube around a Silastic stent. Stage II consisted of creation of a full-thickness circumferential tracheal defect and repair with the flap in those animals in which a suitable rigid tube had been formed. The results of these experiments argue strongly that a vascularized composite pleuroperiosteal flap can produce an adequate tracheal replacement.

Original languageEnglish
Pages (from-to)610-614
Number of pages5
JournalOtolaryngology - Head and Neck Surgery
Issue number6
StatePublished - Dec 1983


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