5 Scopus citations

Abstract

Advancements in regenerative medicine have brought to the fore the need for increased standardization and sharing of stem cell product characterization to help drive these innovative interventions toward public availability. Although numerous attempts have been made to store this data, there is still a lack of a platform that incorporates heterogeneous stem cell information into a harmonized project-based framework. The aim of this project was to introduce and pilot-test an intelligent informatics solution which integrates diverse stem cell product characteristics with study subject and omics information. In the resulting platform, heterogeneous data is validated using predefined ontologies and stored in a NoSQL repository. Pilot-testing was performed on nine sponsored stem cell projects conducting preclinical and intervention evaluations. The pilot-testing demonstrated the robustness of the proposed platform, by seamlessly harmonizing diverse common data elements, and the potential of this platform for driving knowledge generation from the aggregation of this shared data.

Original languageEnglish
Title of host publicationTHE IMPORTANCE OF HEALTH INFORMATICS IN PUBLIC HEALTH DURING A PANDEMIC
EditorsJohn Mantas, Arie Hasman, Mowafa S. Househ, Parisis Gallos, Emmanouil Zoulias
PublisherIOS Press
Pages334-337
Number of pages4
ISBN (Electronic)9781643680927
DOIs
StatePublished - 2020

Publication series

NameStudies in Health Technology and Informatics
Volume272
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Keywords

  • Data aggregation
  • common data elements
  • regenerative medicine
  • stem cells

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