Towards a molecular understanding of hair loss and its treatment

George Cotsarelis, Sarah E. Millar

Research output: Contribution to journalReview articlepeer-review

235 Scopus citations


Most common forms of hair loss (alopecia) are caused by aberrant hair follicle cycling and changes in hair follicle morphology. However, current treatments for alopecia do not specifically target these processes. We are now beginning to identify the molecules and molecular pathways that control normal hair follicle formation, cycling and growth. In parallel, new techniques are being developed for delivering molecules to hair follicles. Here, we outline the characteristics of common hair loss diseases, and discuss ways in which recent advances in hair follicle biology could be translated into effective therapies for these conditions.

Original languageEnglish
Pages (from-to)293-301
Number of pages9
JournalTrends in Molecular Medicine
Issue number7
StatePublished - 2001
Externally publishedYes


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