Towards a molecular classification of illness: Effects of schizophrenia susceptibility loci on clinical symptoms and cognitive function

Anil K. Malhotra, Pamela De Rosse, Katherine E. Burdick

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Schizophrenia is a complex neuropsychiatric disorder characterized by a myriad of symptoms that include hallucinations, delusions, thought disorganization (or positive symptoms), apathy, avolition, and asociality (or negative symptoms), and cognitive impairment. No single symptom, or symptom cluster, is pathognomonic, and the current classification of the disorder into the Diagnostic and Statistical Manual IV (DSM-IV) (First et al. 1997) subtypes of paranoid, disorganized, catatonic and undifferentiated is solely based upon clinical phenomena.

Original languageEnglish
Title of host publicationCortical Deficits in Schizophrenia
Subtitle of host publicationFrom Genes to Function
PublisherSpringer US
Pages17-28
Number of pages12
ISBN (Electronic)9780387743516
ISBN (Print)9780387743509
DOIs
StatePublished - 2008
Externally publishedYes

Fingerprint

Dive into the research topics of 'Towards a molecular classification of illness: Effects of schizophrenia susceptibility loci on clinical symptoms and cognitive function'. Together they form a unique fingerprint.

Cite this