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Toward a responsible future: recommendations for AI-enabled clinical decision support

  • Steven Labkoff
  • , Bilikis Oladimeji
  • , Joseph Kannry
  • , Anthony Solomonides
  • , Russell Leftwich
  • , Eileen Koski
  • , Amanda L. Joseph
  • , Monica Lopez-Gonzalez
  • , Lee A. Fleisher
  • , Kimberly Nolen
  • , Sayon Dutta
  • , Deborah R. Levy
  • , Amy Price
  • , Paul J. Barr
  • , Jonathan D. Hron
  • , Baihan Lin
  • , Gyana Srivastava
  • , Nuria Pastor
  • , Unai Sanchez Luque
  • , Tien Thi Thuy Bui
  • Reva Singh, Tayler Williams, Mark G. Weiner, Tristan Naumann, Dean F. Sittig, Gretchen Purcell Jackson, Yuri Quintana

Research output: Contribution to journalArticlepeer-review

115 Scopus citations

Abstract

Background: Integrating artificial intelligence (AI) in healthcare settings has the potential to benefit clinical decision-making. Addressing challenges such as ensuring trustworthiness, mitigating bias, and maintaining safety is paramount. The lack of established methodologies for pre- and post-deployment evaluation of AI tools regarding crucial attributes such as transparency, performance monitoring, and adverse event reporting makes this situation challenging. Objectives: This paper aims to make practical suggestions for creating methods, rules, and guidelines to ensure that the development, testing, supervision, and use of AI in clinical decision support (CDS) systems are done well and safely for patients. Materials and Methods: In May 2023, the Division of Clinical Informatics at Beth Israel Deaconess Medical Center and the American Medical Informatics Association co-sponsored a working group on AI in healthcare. In August 2023, there were 4 webinars on AI topics and a 2-day workshop in September 2023 for consensus-building. The event included over 200 industry stakeholders, including clinicians, software developers, academics, ethicists, attorneys, government policy experts, scientists, and patients. The goal was to identify challenges associated with the trusted use of AI-enabled CDS in medical practice. Key issues were identified, and solutions were proposed through qualitative analysis and a 4-month iterative consensus process. Results: Our work culminated in several key recommendations: (1) building safe and trustworthy systems; (2) developing validation, verification, and certification processes for AI-CDS systems; (3) providing a means of safety monitoring and reporting at the national level; and (4) ensuring that appropriate documentation and end-user training are provided.

Original languageEnglish
Pages (from-to)2730-2739
Number of pages10
JournalJournal of the American Medical Informatics Association
Volume31
Issue number11
DOIs
StatePublished - 1 Nov 2024

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