Topical Vehicle Formulations in the Treatment of Acne

Lauren K. Hoffman, Neal Bhatia, Joshua Zeichner, Leon H. Kircik

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations

Abstract

Topical treatment is the mainstay of acne therapy. The most commonly prescribed topical medications for acne include benzoyl peroxide, clindamycin, and retinoids. Despite their effectiveness in treating mild to moderate acne vulgaris, these topical medications are found to be irritating, and are historically associated with poor tolerability and diminished patient adherence. Thus, choosing the right formulation that will be effective and well tolerated is essential. Novel formulations that optimize drug concentration and utilize improved delivery vehicles have helped to enhance the tolerability and efficacy, and allow for less frequent application or co-application of drugs that were previously considered incompatible. This article will review the goals of topical therapy for the treatment of acne, in addition to common therapies and their challenges. Advanced formulations and combination formulations of benzoyl peroxide, clindamycin, and tretinoin will also be discussed. J Drugs Dermatol. 2018;17(6 Suppl):s6-10.

Original languageEnglish
Pages (from-to)s6-s10
JournalJournal of Drugs in Dermatology
Volume17
Issue number6
StatePublished - 1 Jun 2018

Fingerprint

Dive into the research topics of 'Topical Vehicle Formulations in the Treatment of Acne'. Together they form a unique fingerprint.

Cite this