Topical treatments for hypertrophic scars

Joanna M. Zurada, David Kriegel, Ira C. Davis

Research output: Contribution to journalArticlepeer-review

155 Scopus citations

Abstract

Hypertrophic scars represent an abnormal, exaggerated healing response after skin injury. In addition to cosmetic concern, scars may cause pain, pruritus, contractures, and other functional impairments. Therapeutic modalities include topical medications, intralesional corticosteroids, laser therapy, and cryosurgery. Topical therapies, in particular, have become increasingly popular because of their ease of use, comfort, noninvasiveness, and relatively low cost. This review will discuss the properties and effectiveness of these agents, including pressure therapy, silicone gel sheeting and ointment, polyurethane dressing, onion extract, imiquimod 5% cream, and vitamins A and E in the prevention and treatment of hypertrophic scars.

Original languageEnglish
Pages (from-to)1024-1031
Number of pages8
JournalJournal of the American Academy of Dermatology
Volume55
Issue number6
DOIs
StatePublished - Dec 2006
Externally publishedYes

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