Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity

Hirofumi Morishita; Manish Arora

doi:10.1016/j.tins.2016.11.003

Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity

Hirofumi Morishita, Manish Arora

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

Developmental brain plasticity involves complex, time-dependent dynamic molecular interactions that cannot be observed directly in humans. We propose that the shared evolutionary homology of teeth and the neurosensory system, and the archival nature of dentine microstructure, allows the development of ‘biologic hard drives’ that can characterize perinatal temporal dynamics in neuroplasticity.

Original language	English
Pages (from-to)	1-3
Number of pages	3
Journal	Trends in Neurosciences
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/j.tins.2016.11.003
State	Published - 1 Jan 2017

Keywords

biomarker
brain plasticity
critical period
teeth

Access to Document

10.1016/j.tins.2016.11.003

Cite this

@article{b356e703243c4042990d2cf168560092,

title = "Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity",

abstract = "Developmental brain plasticity involves complex, time-dependent dynamic molecular interactions that cannot be observed directly in humans. We propose that the shared evolutionary homology of teeth and the neurosensory system, and the archival nature of dentine microstructure, allows the development of {\textquoteleft}biologic hard drives{\textquoteright} that can characterize perinatal temporal dynamics in neuroplasticity.",

keywords = "biomarker, brain plasticity, critical period, teeth",

author = "Hirofumi Morishita and Manish Arora",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Ltd",

year = "2017",

month = jan,

day = "1",

doi = "10.1016/j.tins.2016.11.003",

language = "English",

volume = "40",

pages = "1--3",

journal = "Trends in Neurosciences",

issn = "0378-5912",

publisher = "Elsevier Ltd.",

number = "1",

}

TY - JOUR

T1 - Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity

AU - Morishita, Hirofumi

AU - Arora, Manish

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Developmental brain plasticity involves complex, time-dependent dynamic molecular interactions that cannot be observed directly in humans. We propose that the shared evolutionary homology of teeth and the neurosensory system, and the archival nature of dentine microstructure, allows the development of ‘biologic hard drives’ that can characterize perinatal temporal dynamics in neuroplasticity.

AB - Developmental brain plasticity involves complex, time-dependent dynamic molecular interactions that cannot be observed directly in humans. We propose that the shared evolutionary homology of teeth and the neurosensory system, and the archival nature of dentine microstructure, allows the development of ‘biologic hard drives’ that can characterize perinatal temporal dynamics in neuroplasticity.

KW - biomarker

KW - brain plasticity

KW - critical period

KW - teeth

UR - http://www.scopus.com/inward/record.url?scp=85007557214&partnerID=8YFLogxK

U2 - 10.1016/j.tins.2016.11.003

DO - 10.1016/j.tins.2016.11.003

M3 - Short survey

C2 - 28038829

AN - SCOPUS:85007557214

SN - 0378-5912

VL - 40

SP - 1

EP - 3

JO - Trends in Neurosciences

JF - Trends in Neurosciences

IS - 1

ER -

Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity

Abstract

Keywords

Access to Document

Fingerprint

Cite this