Tofacitinib as a Rescue Therapy for Ulcerative Colitis in Pregnancy

Catherine Rowan; Fiona Yeaman; Kenneth Ernest-Suarez; Marie Louise Martin; Remo Panaccione; Tushar Shukla; Matt Grossi; Meghan Vlasschaert; Kerri Novak; Cynthia Seow

doi:10.1093/ibd/izae076

Tofacitinib as a Rescue Therapy for Ulcerative Colitis in Pregnancy

Catherine Rowan, Fiona Yeaman, Kenneth Ernest-Suarez, Marie Louise Martin, Remo Panaccione, Tushar Shukla, Matt Grossi, Meghan Vlasschaert, Kerri Novak, Cynthia Seow

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Tofacitinib, a potentially teratogenic nonselective Janus Kinase inhibitor was used as salvage therapy for ulcerative colitis during pregnancy with corticosteroids, maintenance ustekinumab, and rectal 5-ASA therapy. Corticosteroid-free remission ensued, resulting in term delivery without congenital malformations and avoidance of colectomy.

Original language	English
Pages (from-to)	868-870
Number of pages	3
Journal	Inflammatory Bowel Diseases
Volume	30
Issue number	5
DOIs	https://doi.org/10.1093/ibd/izae076
State	Published - 1 May 2024
Externally published	Yes

Keywords

pregnancy
tofacitinib
ulcerative colitis

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10.1093/ibd/izae076

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abstract = "Tofacitinib, a potentially teratogenic nonselective Janus Kinase inhibitor was used as salvage therapy for ulcerative colitis during pregnancy with corticosteroids, maintenance ustekinumab, and rectal 5-ASA therapy. Corticosteroid-free remission ensued, resulting in term delivery without congenital malformations and avoidance of colectomy.",

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AU - Rowan, Catherine

AU - Yeaman, Fiona

AU - Ernest-Suarez, Kenneth

AU - Martin, Marie Louise

AU - Panaccione, Remo

AU - Shukla, Tushar

AU - Grossi, Matt

AU - Vlasschaert, Meghan

AU - Novak, Kerri

AU - Seow, Cynthia

PY - 2024/5/1

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AB - Tofacitinib, a potentially teratogenic nonselective Janus Kinase inhibitor was used as salvage therapy for ulcerative colitis during pregnancy with corticosteroids, maintenance ustekinumab, and rectal 5-ASA therapy. Corticosteroid-free remission ensued, resulting in term delivery without congenital malformations and avoidance of colectomy.

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KW - ulcerative colitis

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ER -

Tofacitinib as a Rescue Therapy for Ulcerative Colitis in Pregnancy

Abstract

Keywords

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