Tissue concentrations of free amino acids in term human placentas

A. F. Philipps; I. R. Holzman; C. Teng; F. C. Battaglia

doi:10.1016/S0002-9378(16)33136-2

Tissue concentrations of free amino acids in term human placentas

A. F. Philipps, I. R. Holzman, C. Teng, F. C. Battaglia

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Abstract

Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via ¹⁴C inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5 μmoles per gram wet weight.

Original language	English
Pages (from-to)	881-887
Number of pages	7
Journal	American Journal of Obstetrics and Gynecology
Volume	131
Issue number	8
DOIs	https://doi.org/10.1016/S0002-9378(16)33136-2
State	Published - 1978
Externally published	Yes

Access to Document

10.1016/S0002-9378(16)33136-2

Cite this

@article{7b73b3eb96a04f5bb1d5226f42721d8e,

title = "Tissue concentrations of free amino acids in term human placentas",

abstract = "Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5 μmoles per gram wet weight.",

author = "Philipps, {A. F.} and Holzman, {I. R.} and C. Teng and Battaglia, {F. C.}",

note = "Funding Information: Supported by United States Public Health Service Grants HD-00781 and HD-00429.",

year = "1978",

doi = "10.1016/S0002-9378(16)33136-2",

language = "English",

volume = "131",

pages = "881--887",

journal = "American Journal of Obstetrics and Gynecology",

issn = "0002-9378",

publisher = "Mosby Inc.",

number = "8",

}

TY - JOUR

T1 - Tissue concentrations of free amino acids in term human placentas

AU - Philipps, A. F.

AU - Holzman, I. R.

AU - Teng, C.

AU - Battaglia, F. C.

N1 - Funding Information: Supported by United States Public Health Service Grants HD-00781 and HD-00429.

PY - 1978

Y1 - 1978

N2 - Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5 μmoles per gram wet weight.

AB - Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5 μmoles per gram wet weight.

UR - http://www.scopus.com/inward/record.url?scp=0017857671&partnerID=8YFLogxK

U2 - 10.1016/S0002-9378(16)33136-2

DO - 10.1016/S0002-9378(16)33136-2

M3 - Article

C2 - 686088

AN - SCOPUS:0017857671

VL - 131

SP - 881

EP - 887

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 8

ER -

Tissue concentrations of free amino acids in term human placentas

Abstract

Access to Document

Fingerprint

Cite this