Timing is everything? Reconciling the results of recent trials in acute kidney injury

Christina M. Wyatt, Steven G. Coca

Research output: Contribution to journalComment/debate

1 Scopus citations

Abstract

Observational studies have failed to establish the optimal timing of renal replacement therapy in critically ill adults with acute kidney injury, with some studies suggesting benefit and others suggesting the potential for harm with earlier initiation. Two recent randomized trials have addressed this controversy, also with conflicting results. Careful consideration of differences between the 2 studies is essential when applying the results to clinical practice in the intensive care unit.

Original languageEnglish
Pages (from-to)718-721
Number of pages4
JournalKidney International
Volume90
Issue number4
DOIs
StatePublished - 1 Oct 2016

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