Thyroid adenoma following treatment of acute lymphocytic leukemia

Robert Rapaport, Akira Morishima, James A. Wolff, Beverly Ryan, Thomas R. Walters

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Sequelae of the treatment of children with acute lymphocytic leukemia (ALL) include multiple effects on the endocrine system, especially as it relates to growth and puberty. Thyroid dysfunction, and in particular, the occurrence of thyroid neoplasia, has been only rarely described. We report the development of benign thyroid neoplasms in two patients 9 years following the diagnosis and treatment of ALL. Both patients were clinically and biochemically euthyroid with noncystic “cold” nodules found on thyroid scan. In light of these observations, and along with previous reports of malignant thyroid neoplasia in children with ALL, long-term careful observation of children successfully treated for ALL is indicated.

Original languageEnglish
Pages (from-to)190-193
Number of pages4
JournalAmerican Journal of Pediatric Hematology/Oncology
Issue number2
StatePublished - 1990
Externally publishedYes


  • ALL treatment
  • Thyroid adenoma


Dive into the research topics of 'Thyroid adenoma following treatment of acute lymphocytic leukemia'. Together they form a unique fingerprint.

Cite this