Thymectomy in patients more than forty years of age with myasthenia gravis

G. Slater, A. E. Papatestas, G. Genkins, P. Kornfeld, S. H. Horowitz

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Until recently, thymectomy has been reserved for patients with myasthenia gravis in the younger age groups. The use of transcervical thymectomy, with its reduction in morbidity and mortality, has allowed us to study the effects of thymectomy in the older age group. The records of 525 patients who underwent thymectomy were reviewed and divided into two groups: those less than and those more than 40 years of age. The incidence of thymomas was greatest in the older than 40 year group. This age group without thymoma was also noted to have a high incidence of absent germinal centers. The postoperative remission rates as well as the electromyographic improvement rates were comparable for both age groups. The evidence presented indicates that thymectomy improves the clinical course of myasthenia gravis in all age groups studied. The authors recommend transcervical thymectomy for all patients with generalized myasthenia gravis, regardless of age.

Original languageEnglish
Pages (from-to)54-56
Number of pages3
JournalSurgery Gynecology and Obstetrics
Volume146
Issue number1
StatePublished - 1978
Externally publishedYes

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