Thulium fiber laser utilization in urological surgery: A narrative review

Johnathan A. Khusid, Raymond Khargi, Benjamin Seiden, Areeba S. Sadiq, William M. Atallah, Mantu Gupta

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

The thulium fiber laser (TFL) is a novel technology under active investigation as an conceivable alternative to the Holmium:yttrium-aluminum-garnet (Ho:YAG) laser, which is currently the gold standard for an array of urologic procedures. The purpose of this review is to discuss the existing literature on the functionality and effectiveness of TFL in urological practice. We conducted a search of the PubMed, Medline, Web of Science Core Collection, SCOPUS, Embase (OVID), and Cochrane Databases for all full articles and systematic reviews on the TFL. We found a total of 35 relevant pieces of literature. The early research findings pertaining to the TFL exhibit numerous potential advantages over the Ho:YAG laser. In vitro and ex vivo studies have highlighted the TFL’s ability to utilize smaller laser fibers, obtain faster stone ablation rates, and achieve less retropulsion when tested against the Ho:YAG laser in lithotripsy. Currently, there is limited in vivo research that investigates the utilization of the TFL. The in vivo results that are avail-able, however, look promising both for laser lithotripsy and soft tissue ablation. Indeed, the existing literature suggests that the TFL has great potential and may possess numerous technological advantages over the Ho:YAG laser, especially in laser lithotripsy. Al-though these early studies are promising, randomized control trials are needed to assess the full applicability of the TFL in urology.

Original languageEnglish
Pages (from-to)136-147
Number of pages12
JournalInvestigative and Clinical Urology
Volume62
Issue number2
DOIs
StatePublished - Mar 2021

Keywords

  • Laser therapy
  • Lithotripsy
  • Surgical endoscopy
  • Thulium
  • Urology

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