Thrombosis in cancer: Research priorities identified by a national cancer institute/national heart, lung, and blood institute strategic working group

Nigel S. Key; Alok A. Khorana; Nigel Mackman; Owen J.T. McCarty; Gilbert C. White; Charles W. Francis; Keith R. McCrae; Joseph S. Palumbo; Gary E. Raskob; Andrew T. Chan; Anil K. Sood

doi:10.1158/0008-5472.CAN-15-3100

Thrombosis in cancer: Research priorities identified by a national cancer institute/national heart, lung, and blood institute strategic working group

Nigel S. Key, Alok A. Khorana, Nigel Mackman, Owen J.T. McCarty, Gilbert C. White, Charles W. Francis, Keith R. McCrae, Joseph S. Palumbo, Gary E. Raskob, Andrew T. Chan, Anil K. Sood

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

The risk for venous thromboembolism (VTE) is increased in cancer and particularly with chemotherapy, and it portends poorer survival among patients with cancer. However, many fundamental questions about cancer-associated VTE, or Trousseau syndrome, remain unanswered. This report summarizes the proceedings of a working group assembled by the NCI and NHLBI in August 2014 to explore the state of the science in cancer-associated VTE, identify clinically important research gaps, and develop consensus on priorities for future research. Representing a convergence of research priorities between the two NIH Institutes, the workshop addressed epidemiologic, basic science, clinical, and translational issues in cancer-associated VTE.

Original language	English
Pages (from-to)	3671-3675
Number of pages	5
Journal	Cancer Research
Volume	76
Issue number	13
DOIs	https://doi.org/10.1158/0008-5472.CAN-15-3100
State	Published - 1 Jul 2016
Externally published	Yes

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Key, N. S., Khorana, A. A., Mackman, N., McCarty, O. J. T., White, G. C., Francis, C. W., McCrae, K. R., Palumbo, J. S., Raskob, G. E., Chan, A. T., & Sood, A. K. (2016). Thrombosis in cancer: Research priorities identified by a national cancer institute/national heart, lung, and blood institute strategic working group. Cancer Research, 76(13), 3671-3675. https://doi.org/10.1158/0008-5472.CAN-15-3100

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title = "Thrombosis in cancer: Research priorities identified by a national cancer institute/national heart, lung, and blood institute strategic working group",

abstract = "The risk for venous thromboembolism (VTE) is increased in cancer and particularly with chemotherapy, and it portends poorer survival among patients with cancer. However, many fundamental questions about cancer-associated VTE, or Trousseau syndrome, remain unanswered. This report summarizes the proceedings of a working group assembled by the NCI and NHLBI in August 2014 to explore the state of the science in cancer-associated VTE, identify clinically important research gaps, and develop consensus on priorities for future research. Representing a convergence of research priorities between the two NIH Institutes, the workshop addressed epidemiologic, basic science, clinical, and translational issues in cancer-associated VTE.",

author = "Key, {Nigel S.} and Khorana, {Alok A.} and Nigel Mackman and McCarty, {Owen J.T.} and White, {Gilbert C.} and Francis, {Charles W.} and McCrae, {Keith R.} and Palumbo, {Joseph S.} and Raskob, {Gary E.} and Chan, {Andrew T.} and Sood, {Anil K.}",

note = "Publisher Copyright: {\textcopyright} 2016 AACR.",

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doi = "10.1158/0008-5472.CAN-15-3100",

language = "English",

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Key, NS, Khorana, AA, Mackman, N, McCarty, OJT, White, GC, Francis, CW, McCrae, KR, Palumbo, JS, Raskob, GE, Chan, AT & Sood, AK 2016, 'Thrombosis in cancer: Research priorities identified by a national cancer institute/national heart, lung, and blood institute strategic working group', Cancer Research, vol. 76, no. 13, pp. 3671-3675. https://doi.org/10.1158/0008-5472.CAN-15-3100

TY - JOUR

T1 - Thrombosis in cancer

T2 - Research priorities identified by a national cancer institute/national heart, lung, and blood institute strategic working group

AU - Key, Nigel S.

AU - Khorana, Alok A.

AU - Mackman, Nigel

AU - McCarty, Owen J.T.

AU - White, Gilbert C.

AU - Francis, Charles W.

AU - McCrae, Keith R.

AU - Palumbo, Joseph S.

AU - Raskob, Gary E.

AU - Chan, Andrew T.

AU - Sood, Anil K.

PY - 2016/7/1

Y1 - 2016/7/1

N2 - The risk for venous thromboembolism (VTE) is increased in cancer and particularly with chemotherapy, and it portends poorer survival among patients with cancer. However, many fundamental questions about cancer-associated VTE, or Trousseau syndrome, remain unanswered. This report summarizes the proceedings of a working group assembled by the NCI and NHLBI in August 2014 to explore the state of the science in cancer-associated VTE, identify clinically important research gaps, and develop consensus on priorities for future research. Representing a convergence of research priorities between the two NIH Institutes, the workshop addressed epidemiologic, basic science, clinical, and translational issues in cancer-associated VTE.

AB - The risk for venous thromboembolism (VTE) is increased in cancer and particularly with chemotherapy, and it portends poorer survival among patients with cancer. However, many fundamental questions about cancer-associated VTE, or Trousseau syndrome, remain unanswered. This report summarizes the proceedings of a working group assembled by the NCI and NHLBI in August 2014 to explore the state of the science in cancer-associated VTE, identify clinically important research gaps, and develop consensus on priorities for future research. Representing a convergence of research priorities between the two NIH Institutes, the workshop addressed epidemiologic, basic science, clinical, and translational issues in cancer-associated VTE.

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U2 - 10.1158/0008-5472.CAN-15-3100

DO - 10.1158/0008-5472.CAN-15-3100

M3 - Article

C2 - 27527638

AN - SCOPUS:84977522286

SN - 0008-5472

VL - 76

SP - 3671

EP - 3675

JO - Cancer Research

JF - Cancer Research

IS - 13

ER -

Thrombosis in cancer: Research priorities identified by a national cancer institute/national heart, lung, and blood institute strategic working group

Abstract

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