Thromboelastometry-guided neuraxial anesthesia in a parturient with severe thrombocytopenia due to large granular lymphocytic leukemia

Chloe Getrajdman; Matthew Sison; Colleen Yen; Morgane Giordano; Yaakov Beilin; Daniel Katz

doi:10.1097/MBC.0000000000000970

Thromboelastometry-guided neuraxial anesthesia in a parturient with severe thrombocytopenia due to large granular lymphocytic leukemia

Chloe Getrajdman
, Matthew Sison
, Colleen Yen
, Morgane Giordano
, Yaakov Beilin
, Daniel Katz

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Severe thrombocytopenia (platelet count <50 000/μl) in pregnancy is uncommon and is generally considered a contraindication to neuraxial anesthesia. We present a case of a parturient who presented with severe thrombocytopenia secondary to bone marrow failure. After receiving platelet and cryoprecipitate transfusions to correct coagulopathy as verified by thromboelastometry, neuraxial anesthesia was safely utilized.

Original language	English
Pages (from-to)	64-67
Number of pages	4
Journal	Blood Coagulation and Fibrinolysis
Volume	32
Issue number	1
DOIs	https://doi.org/10.1097/MBC.0000000000000970
State	Published - 1 Jan 2021

Keywords

large granular lymphocytic leukemia
neuraxial anesthesia
thrombocytopenia
thromboelastometry

Access to Document

10.1097/MBC.0000000000000970

Cite this

@article{30e4384558544f73b1dd48caa74e3899,

title = "Thromboelastometry-guided neuraxial anesthesia in a parturient with severe thrombocytopenia due to large granular lymphocytic leukemia",

abstract = "Severe thrombocytopenia (platelet count <50 000/μl) in pregnancy is uncommon and is generally considered a contraindication to neuraxial anesthesia. We present a case of a parturient who presented with severe thrombocytopenia secondary to bone marrow failure. After receiving platelet and cryoprecipitate transfusions to correct coagulopathy as verified by thromboelastometry, neuraxial anesthesia was safely utilized.",

keywords = "large granular lymphocytic leukemia, neuraxial anesthesia, thrombocytopenia, thromboelastometry",

author = "Chloe Getrajdman and Matthew Sison and Colleen Yen and Morgane Giordano and Yaakov Beilin and Daniel Katz",

year = "2021",

month = jan,

day = "1",

doi = "10.1097/MBC.0000000000000970",

language = "English",

volume = "32",

pages = "64--67",

journal = "Blood Coagulation and Fibrinolysis",

issn = "0957-5235",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

TY - JOUR

T1 - Thromboelastometry-guided neuraxial anesthesia in a parturient with severe thrombocytopenia due to large granular lymphocytic leukemia

AU - Getrajdman, Chloe

AU - Sison, Matthew

AU - Yen, Colleen

AU - Giordano, Morgane

AU - Beilin, Yaakov

AU - Katz, Daniel

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Severe thrombocytopenia (platelet count <50 000/μl) in pregnancy is uncommon and is generally considered a contraindication to neuraxial anesthesia. We present a case of a parturient who presented with severe thrombocytopenia secondary to bone marrow failure. After receiving platelet and cryoprecipitate transfusions to correct coagulopathy as verified by thromboelastometry, neuraxial anesthesia was safely utilized.

AB - Severe thrombocytopenia (platelet count <50 000/μl) in pregnancy is uncommon and is generally considered a contraindication to neuraxial anesthesia. We present a case of a parturient who presented with severe thrombocytopenia secondary to bone marrow failure. After receiving platelet and cryoprecipitate transfusions to correct coagulopathy as verified by thromboelastometry, neuraxial anesthesia was safely utilized.

KW - large granular lymphocytic leukemia

KW - neuraxial anesthesia

KW - thrombocytopenia

KW - thromboelastometry

UR - https://www.scopus.com/pages/publications/85100070347

U2 - 10.1097/MBC.0000000000000970

DO - 10.1097/MBC.0000000000000970

M3 - Article

C2 - 33196515

AN - SCOPUS:85100070347

SN - 0957-5235

VL - 32

SP - 64

EP - 67

JO - Blood Coagulation and Fibrinolysis

JF - Blood Coagulation and Fibrinolysis

IS - 1

ER -

Thromboelastometry-guided neuraxial anesthesia in a parturient with severe thrombocytopenia due to large granular lymphocytic leukemia

Abstract

Keywords

Access to Document

Fingerprint

Cite this