Thoracoabdominal Aortic Disease and Repair: JACC Focus Seminar, Part 3

Maral Ouzounian, Rami O. Tadros, Lars G. Svensson, Sean P. Lyden, Gustavo S. Oderich, Joseph S. Coselli

Research output: Contribution to journalReview articlepeer-review


Thoracoabdominal aortic disease is a rare but life-threatening condition that requires expert multidisciplinary collaborative management. Intervention is indicated in patients with symptomatic aneurysms or when an aneurysm reaches a certain threshold of diameter or rate of expansion. The strategies for spinal cord and end-organ protection have evolved over several decades, resulting in improved outcomes after repair. Open repair, although invasive, provides definitive and durable repair. Endovascular approaches are rapidly evolving, and the results with fenestrated and branched endografts are promising. Both open repair and endovascular repair require highly specialized expertise, and outcomes are best when repair is undertaken in an elective setting by a dedicated team. Patients with degenerative thoracoabdominal aortic aneurysms and chronic dissections should be followed up closely and referred for elective repair when indicated.

Original languageEnglish
Pages (from-to)845-856
Number of pages12
JournalJournal of the American College of Cardiology
Issue number8
StatePublished - 23 Aug 2022


  • aortic aneurysm
  • dissection
  • endovascular
  • thoracoabdominal aneurysm


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