Therapeutic monitoring of immunotherapies in autoimmune diseases

Nicolas von Ahsen, Andrew Chan

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Immunosuppressive treatment still is an important element in the management of autoimmune mediated diseases. However, immunosuppressive therapy is often complicated by a narrow therapeutic index and high variability of treatment response. This review discusses the clinical management and monitoring strategies for the use of ciclosporin A, tacrolimus, azathioprine, mycophenolat mofetil, mitoxantrone and some monoclonal antibodies with focus on natalizumab.

Original languageEnglish
Pages (from-to)4550-4555
Number of pages6
JournalCurrent Pharmaceutical Design
Volume18
Issue number29
DOIs
StatePublished - 2012
Externally publishedYes

Keywords

  • Azathioprine
  • Ciclosporin a
  • Mitoxantrone
  • Mycophenolat mofetil
  • Natalizumab
  • Neuroimmunology
  • Therapeutic drug monitoring

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