Therapeutic efficacy of human monoclonal antibodies against andes virus infection in syrian hamsters

Brandi N. Williamson, Joseph Prescott, Jose L. Garrido, Raymond A. Alvarez, Heinz Feldmann, Maria I. Barría

Research output: Contribution to journalArticlepeer-review

Abstract

Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. We show that a combined treatment with 2 monoclonal antibodies protected Syrian hamsters when administered at midstage or late-stage disease.

Original languageEnglish
Pages (from-to)2707-2710
Number of pages4
JournalEmerging Infectious Diseases
Volume27
Issue number10
DOIs
StatePublished - Oct 2021
Externally publishedYes

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