The utility of the TDx test in the assessment of fetal lung maturity

J. D. Steinfeld, P. Samuels, M. A. Bulley, A. W. Cohen, D. B.P. Goodman, M. B. Senior

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Accurate assessment of fetal lung maturity is essential in the management of high-risk obstetric patients. New rapid techniques have been developed to supplement time-consuming chromatographic methods. We compared one of these newer methods, the TDx-FLM, to the standard tests for fetal pulmonary maturity. There was an excellent correlation between the TDx and the lecithin-sphingomyelin ratio (r = 0.78). Although a TDx value of 70 or greater is considered mature, we found a value of 50 or greater predictive of fetal lung maturity in 100% of cases, and have chosen to redefine a mature value as 30 or greater in our institution. This value has greatly enhanced the clinical applicability of the test, allowing use of a large number of specimens from the previously poorly understood and often disregarded borderline category.

Original languageEnglish
Pages (from-to)460-464
Number of pages5
JournalObstetrics and Gynecology
Volume79
Issue number3
DOIs
StatePublished - 1992
Externally publishedYes

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