TY - JOUR
T1 - The Utility of Bronchoscopy in Hydralazine-Induced ANCA-Associated Vasculitis
AU - Khosla, Atulya Aman
AU - Saunders, Hollie
AU - Helgeson, Scott
AU - Hikida, Hiroshi
AU - Aslam, Nabeel
AU - Salem, Fadi
AU - Albadri, Sam
AU - Baig, Hassan
N1 - Publisher Copyright:
© 2023 Atulya Aman Khosla et al.
PY - 2023
Y1 - 2023
N2 - Hydralazine is a vasodilator used for the management of hypertension, heart failure, and hypertensive emergencies in pregnancy. It has been implicated in the causation of drug-induced lupus erythematosus (DLE) and rarely with ANCA-associated vasculitis (AAV), which may present as a pulmonary-renal syndrome and be rapidly fatal. Herein, we describe a case of hydralazine-associated AAV presenting as acute kidney injury with the use of early bronchoalveolar lavage (BAL) with serial aliquots to aid with diagnosis. Our case highlights how, in the correct clinical setting, BAL can act as a rapid diagnostic test to help guide quicker treatment to allow for better patient outcomes.
AB - Hydralazine is a vasodilator used for the management of hypertension, heart failure, and hypertensive emergencies in pregnancy. It has been implicated in the causation of drug-induced lupus erythematosus (DLE) and rarely with ANCA-associated vasculitis (AAV), which may present as a pulmonary-renal syndrome and be rapidly fatal. Herein, we describe a case of hydralazine-associated AAV presenting as acute kidney injury with the use of early bronchoalveolar lavage (BAL) with serial aliquots to aid with diagnosis. Our case highlights how, in the correct clinical setting, BAL can act as a rapid diagnostic test to help guide quicker treatment to allow for better patient outcomes.
UR - http://www.scopus.com/inward/record.url?scp=85156127447&partnerID=8YFLogxK
U2 - 10.1155/2023/1461011
DO - 10.1155/2023/1461011
M3 - Article
AN - SCOPUS:85156127447
SN - 2090-6846
VL - 2023
JO - Case Reports in Pulmonology
JF - Case Reports in Pulmonology
M1 - 1461011
ER -