TY - JOUR
T1 - The tyrosine peptides of HLA and β2 microglobulin
AU - Cunningham Rundles, C.
AU - Dupont, B.
AU - Jersild, C.
AU - Good, R. A.
PY - 1977
Y1 - 1977
N2 - A study of the HLA tyrosine peptides has now been extended to a second-dimensional electrophoresis: and using pure β2-microglobulin, it is possible to identify which peptides of the HLA complex are contributed by this small component. It appears that iodinated cell surface antigens may be examined by these electrophoretic methods in order to determine the extent of possible homology that may exist between them. The seven radioactive peptides produced from β2-m have been studied in a similar manner, and it appears that peptides 1, 3, 6, and 7 of β2-m have similar electrophoretic behavior in a variety of electrophoretic experiments to four peptides present in the HLA antigen complex. It appears probable that these HLA peptides are, in fact, contributed by β2-m.
AB - A study of the HLA tyrosine peptides has now been extended to a second-dimensional electrophoresis: and using pure β2-microglobulin, it is possible to identify which peptides of the HLA complex are contributed by this small component. It appears that iodinated cell surface antigens may be examined by these electrophoretic methods in order to determine the extent of possible homology that may exist between them. The seven radioactive peptides produced from β2-m have been studied in a similar manner, and it appears that peptides 1, 3, 6, and 7 of β2-m have similar electrophoretic behavior in a variety of electrophoretic experiments to four peptides present in the HLA antigen complex. It appears probable that these HLA peptides are, in fact, contributed by β2-m.
UR - http://www.scopus.com/inward/record.url?scp=0017340530&partnerID=8YFLogxK
M3 - Article
C2 - 67677
AN - SCOPUS:0017340530
SN - 0041-1345
VL - 9
SP - 29
EP - 32
JO - Transplantation Proceedings
JF - Transplantation Proceedings
IS - 1 sup.I
ER -