The twentieth century struggle to decipher insulin signalling

Philip Cohen

doi:10.1038/nrm2043

The twentieth century struggle to decipher insulin signalling

Philip Cohen

Research output: Contribution to journal › Review article › peer-review

193 Scopus citations

Abstract

Following the discovery of insulin, it took the rest of the twentieth century to understand how this hormone regulates intracellular metabolism. What are the main discoveries that led to our current understanding of this process? And how is this new knowledge being exploited in an attempt to develop improved drugs to treat the epidemic of type-2 diabetes?

Original language	English
Pages (from-to)	867-873
Number of pages	7
Journal	Nature Reviews Molecular Cell Biology
Volume	7
Issue number	11
DOIs	https://doi.org/10.1038/nrm2043
State	Published - Nov 2006
Externally published	Yes

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abstract = "Following the discovery of insulin, it took the rest of the twentieth century to understand how this hormone regulates intracellular metabolism. What are the main discoveries that led to our current understanding of this process? And how is this new knowledge being exploited in an attempt to develop improved drugs to treat the epidemic of type-2 diabetes?",

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The twentieth century struggle to decipher insulin signalling

Abstract

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