The synthesis of cholesteryl alkyl ethers

G. Halperin; S. Gatt

doi:10.1016/0039-128X(80)90109-9

The synthesis of cholesteryl alkyl ethers

G. Halperin, S. Gatt

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Seventeen cholesteryl alkyl ethers were synthesized through alcoholysis of cholesterol p-toluenesulfonate. This method was found superior to the etherification of sodium or potassium cholesterylate with alkyl halides or methanesulfonates, especially for the preparation of long-chain unsaturated alkyl ethers of [7(n)-³H]cholesterol of high specific activity.

Original language	English
Pages (from-to)	39-42
Number of pages	4
Journal	Steroids
Volume	35
Issue number	1
DOIs	https://doi.org/10.1016/0039-128X(80)90109-9
State	Published - Jan 1980
Externally published	Yes

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title = "The synthesis of cholesteryl alkyl ethers",

abstract = "Seventeen cholesteryl alkyl ethers were synthesized through alcoholysis of cholesterol p-toluenesulfonate. This method was found superior to the etherification of sodium or potassium cholesterylate with alkyl halides or methanesulfonates, especially for the preparation of long-chain unsaturated alkyl ethers of [7(n)-3H]cholesterol of high specific activity.",

author = "G. Halperin and S. Gatt",

note = "Funding Information: Acknowledgements. We thank Prof. Y. Stein for his encouragement. This work was supported in part by NIH grant NS02967.",

year = "1980",

month = jan,

doi = "10.1016/0039-128X(80)90109-9",

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T1 - The synthesis of cholesteryl alkyl ethers

AU - Halperin, G.

AU - Gatt, S.

N1 - Funding Information: Acknowledgements. We thank Prof. Y. Stein for his encouragement. This work was supported in part by NIH grant NS02967.

PY - 1980/1

Y1 - 1980/1

N2 - Seventeen cholesteryl alkyl ethers were synthesized through alcoholysis of cholesterol p-toluenesulfonate. This method was found superior to the etherification of sodium or potassium cholesterylate with alkyl halides or methanesulfonates, especially for the preparation of long-chain unsaturated alkyl ethers of [7(n)-3H]cholesterol of high specific activity.

AB - Seventeen cholesteryl alkyl ethers were synthesized through alcoholysis of cholesterol p-toluenesulfonate. This method was found superior to the etherification of sodium or potassium cholesterylate with alkyl halides or methanesulfonates, especially for the preparation of long-chain unsaturated alkyl ethers of [7(n)-3H]cholesterol of high specific activity.

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U2 - 10.1016/0039-128X(80)90109-9

DO - 10.1016/0039-128X(80)90109-9

M3 - Article

C2 - 7376210

AN - SCOPUS:0019204662

SN - 0039-128X

VL - 35

SP - 39

EP - 42

JO - Steroids

JF - Steroids

IS - 1

ER -

The synthesis of cholesteryl alkyl ethers

Abstract

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