The syndrome of inappropriate antidiuretic hormone secretion associated with induction chemotherapy for squamous cell carcinoma of the head and neck

Daniel F. Hayes; Ronald M. Lechan; Marshall R. Posner; Ralph R. Weichselbaum; Daniel Miller; Thomas J. Ervin

doi:10.1002/jso.2930320306

The syndrome of inappropriate antidiuretic hormone secretion associated with induction chemotherapy for squamous cell carcinoma of the head and neck

Daniel F. Hayes, Ronald M. Lechan, Marshall R. Posner, Ralph R. Weichselbaum, Daniel Miller, Thomas J. Ervin

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Two patients with squamous cell carcinoma of the head and neck are reported in whom the syndrome of inappropriate antidiuretic hormone (SIADH) secretion occurred transiently during the rapid cytolytic phase of tumor destruction after chemotherapy with cis‐platinum diamminedi‐chloride and bleomycin. Immunoperoxidase staining for ADH of the original biopsy specimens from both patients was negative. Possible mechanisms for and the implications of the production of SIADH in this setting are discussed.

Original language	English
Pages (from-to)	150-152
Number of pages	3
Journal	Journal of Surgical Oncology
Volume	32
Issue number	3
DOIs	https://doi.org/10.1002/jso.2930320306
State	Published - Jul 1986
Externally published	Yes

Keywords

SCC/H&N
SIADH
squamous cancer
tumor necrosis

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title = "The syndrome of inappropriate antidiuretic hormone secretion associated with induction chemotherapy for squamous cell carcinoma of the head and neck",

abstract = "Two patients with squamous cell carcinoma of the head and neck are reported in whom the syndrome of inappropriate antidiuretic hormone (SIADH) secretion occurred transiently during the rapid cytolytic phase of tumor destruction after chemotherapy with cis‐platinum diamminedi‐chloride and bleomycin. Immunoperoxidase staining for ADH of the original biopsy specimens from both patients was negative. Possible mechanisms for and the implications of the production of SIADH in this setting are discussed.",

keywords = "SCC/H&N, SIADH, squamous cancer, tumor necrosis",

author = "Hayes, {Daniel F.} and Lechan, {Ronald M.} and Posner, {Marshall R.} and Weichselbaum, {Ralph R.} and Daniel Miller and Ervin, {Thomas J.}",

year = "1986",

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AU - Hayes, Daniel F.

AU - Lechan, Ronald M.

AU - Posner, Marshall R.

AU - Weichselbaum, Ralph R.

AU - Miller, Daniel

AU - Ervin, Thomas J.

PY - 1986/7

Y1 - 1986/7

N2 - Two patients with squamous cell carcinoma of the head and neck are reported in whom the syndrome of inappropriate antidiuretic hormone (SIADH) secretion occurred transiently during the rapid cytolytic phase of tumor destruction after chemotherapy with cis‐platinum diamminedi‐chloride and bleomycin. Immunoperoxidase staining for ADH of the original biopsy specimens from both patients was negative. Possible mechanisms for and the implications of the production of SIADH in this setting are discussed.

AB - Two patients with squamous cell carcinoma of the head and neck are reported in whom the syndrome of inappropriate antidiuretic hormone (SIADH) secretion occurred transiently during the rapid cytolytic phase of tumor destruction after chemotherapy with cis‐platinum diamminedi‐chloride and bleomycin. Immunoperoxidase staining for ADH of the original biopsy specimens from both patients was negative. Possible mechanisms for and the implications of the production of SIADH in this setting are discussed.

KW - SCC/H&N

KW - SIADH

KW - squamous cancer

KW - tumor necrosis

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ER -

The syndrome of inappropriate antidiuretic hormone secretion associated with induction chemotherapy for squamous cell carcinoma of the head and neck

Abstract

Keywords

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