The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics

Carlos Andrés Chacón-Martínez; Nadine Kiessling; Moritz Winterhoff; Jan Faix; Thomas Müller-Reichert; Rolf Jessberger

doi:10.1074/jbc.M113.461277

The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics

Carlos Andrés Chacón-Martínez
, Nadine Kiessling
, Moritz Winterhoff
, Jan Faix
, Thomas Müller-Reichert
, Rolf Jessberger

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Background:Precise spatiotemporal rearrangement of the actin cytoskeleton is essential for cell migration and adhesion. Results:SWAP-70 bundles actin filaments and interacts with cofilinin vitroand in murine mast cells. Conclusion:SWAP-70 is a parallel and anti-parallel bundling protein that participates in the organization of F-actin networks. Significance: Identification and characterization of a regulator of F-actin dynamics improve our understanding on the spatiotemporal control of cytoskeletal processes.

Original language	English
Pages (from-to)	28687-28703
Number of pages	17
Journal	Journal of Biological Chemistry
Volume	288
Issue number	40
DOIs	https://doi.org/10.1074/jbc.M113.461277
State	Published - 4 Oct 2013
Externally published	Yes

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title = "The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics",

abstract = "Background:Precise spatiotemporal rearrangement of the actin cytoskeleton is essential for cell migration and adhesion. Results:SWAP-70 bundles actin filaments and interacts with cofilinin vitroand in murine mast cells. Conclusion:SWAP-70 is a parallel and anti-parallel bundling protein that participates in the organization of F-actin networks. Significance: Identification and characterization of a regulator of F-actin dynamics improve our understanding on the spatiotemporal control of cytoskeletal processes.",

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T1 - The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics

AU - Chacón-Martínez, Carlos Andrés

AU - Kiessling, Nadine

AU - Winterhoff, Moritz

AU - Faix, Jan

AU - Müller-Reichert, Thomas

AU - Jessberger, Rolf

PY - 2013/10/4

Y1 - 2013/10/4

N2 - Background:Precise spatiotemporal rearrangement of the actin cytoskeleton is essential for cell migration and adhesion. Results:SWAP-70 bundles actin filaments and interacts with cofilinin vitroand in murine mast cells. Conclusion:SWAP-70 is a parallel and anti-parallel bundling protein that participates in the organization of F-actin networks. Significance: Identification and characterization of a regulator of F-actin dynamics improve our understanding on the spatiotemporal control of cytoskeletal processes.

AB - Background:Precise spatiotemporal rearrangement of the actin cytoskeleton is essential for cell migration and adhesion. Results:SWAP-70 bundles actin filaments and interacts with cofilinin vitroand in murine mast cells. Conclusion:SWAP-70 is a parallel and anti-parallel bundling protein that participates in the organization of F-actin networks. Significance: Identification and characterization of a regulator of F-actin dynamics improve our understanding on the spatiotemporal control of cytoskeletal processes.

UR - https://www.scopus.com/pages/publications/84885136108

U2 - 10.1074/jbc.M113.461277

DO - 10.1074/jbc.M113.461277

M3 - Article

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EP - 28703

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 40

ER -

The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics

Abstract

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