6 Scopus citations

Abstract

In this issue of Structure, Wu et al. (2018) report several apo and small-molecule inhibitor-bound structures of the kinase domain of hematopoietic progenitor kinase 1, a ser/thr kinase that functions as an inhibitor of T cell activation. The studies reveal that the HPK1 kinase domain exists as a domain-swapped dimer.

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalStructure
Volume27
Issue number1
DOIs
StatePublished - 2 Jan 2019

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