TY - JOUR
T1 - The Structural Biology Knowledgebase
T2 - A portal to protein structures, sequences, functions, and methods
AU - Gabanyi, Margaret J.
AU - Adams, Paul D.
AU - Arnold, Konstantin
AU - Bordoli, Lorenza
AU - Carter, Lester G.
AU - Flippen-Andersen, Judith
AU - Gifford, Lida
AU - Haas, Juergen
AU - Kouranov, Andrei
AU - McLaughlin, William A.
AU - Micallef, David I.
AU - Minor, Wladek
AU - Shah, Raship
AU - Schwede, Torsten
AU - Tao, Yi Ping
AU - Westbrook, John D.
AU - Zimmerman, Matthew
AU - Berman, Helen M.
N1 - Funding Information:
Acknowledgments The SBKB is a resource center within the Protein Structure Initiative and is supported by grant U01 GM093324-01 from the National Institute of General Medical Sciences.
PY - 2011/7
Y1 - 2011/7
N2 - The Protein Structure Initiative's Structural Biology Knowledgebase (SBKB, URL: http://sbkb.org) is an open web resource designed to turn the products of the structural genomics and structural biology efforts into knowledge that can be used by the biological community to understand living systems and disease. Here we will present examples on how to use the SBKB to enable biological research. For example, a protein sequence or Protein Data Bank (PDB) structure ID search will provide a list of related protein structures in the PDB, associated biological descriptions (annotations), homology models, structural genomics protein target status, experimental protocols, and the ability to order available DNA clones from the PSI:Biology-Materials Repository. A text search will find publication and technology reports resulting from the PSI's high-throughput research efforts. Web tools that aid in research, including a system that accepts protein structure requests from the community, will also be described. Created in collaboration with the Nature Publishing Group, the Structural Biology Knowledgebase monthly update also provides a research library, editorials about new research advances, news, and an events calendar to present a broader view of structural genomics and structural biology.
AB - The Protein Structure Initiative's Structural Biology Knowledgebase (SBKB, URL: http://sbkb.org) is an open web resource designed to turn the products of the structural genomics and structural biology efforts into knowledge that can be used by the biological community to understand living systems and disease. Here we will present examples on how to use the SBKB to enable biological research. For example, a protein sequence or Protein Data Bank (PDB) structure ID search will provide a list of related protein structures in the PDB, associated biological descriptions (annotations), homology models, structural genomics protein target status, experimental protocols, and the ability to order available DNA clones from the PSI:Biology-Materials Repository. A text search will find publication and technology reports resulting from the PSI's high-throughput research efforts. Web tools that aid in research, including a system that accepts protein structure requests from the community, will also be described. Created in collaboration with the Nature Publishing Group, the Structural Biology Knowledgebase monthly update also provides a research library, editorials about new research advances, news, and an events calendar to present a broader view of structural genomics and structural biology.
KW - Protein
KW - Protein production
KW - Structural biology
KW - Structural databases
KW - Structural genomics
KW - Theoretical models
UR - https://www.scopus.com/pages/publications/80054042695
U2 - 10.1007/s10969-011-9106-2
DO - 10.1007/s10969-011-9106-2
M3 - Article
C2 - 21472436
AN - SCOPUS:80054042695
SN - 1345-711X
VL - 12
SP - 45
EP - 54
JO - Journal of Structural and Functional Genomics
JF - Journal of Structural and Functional Genomics
IS - 2
ER -