The SNF/SWI family of global transcriptional activators

Marian Carlson; Brehon C. Laurent

doi:10.1016/0955-0674(94)90032-9

The SNF/SWI family of global transcriptional activators

Marian Carlson
, Brehon C. Laurent

Research output: Contribution to journal › Article › peer-review

248 Scopus citations

Abstract

The yeast SNF/SWI proteins have a global role in transcriptional activation. This set of five proteins assists many gene-specific activators, most likely by altering chromatin structure to relieve repression. Recent work shows that the SNF/SWI proteins function together in a multiprotein complex and that SNF2 has DNA-dependent ATPase activity. SNF/SWI homologs have now been identified in Drosophila, mice and humans, suggesting a conserved role in transcriptional activation.

Original language	English
Pages (from-to)	396-402
Number of pages	7
Journal	Current Opinion in Cell Biology
Volume	6
Issue number	3
DOIs	https://doi.org/10.1016/0955-0674(94)90032-9
State	Published - Jun 1994
Externally published	Yes

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title = "The SNF/SWI family of global transcriptional activators",

abstract = "The yeast SNF/SWI proteins have a global role in transcriptional activation. This set of five proteins assists many gene-specific activators, most likely by altering chromatin structure to relieve repression. Recent work shows that the SNF/SWI proteins function together in a multiprotein complex and that SNF2 has DNA-dependent ATPase activity. SNF/SWI homologs have now been identified in Drosophila, mice and humans, suggesting a conserved role in transcriptional activation.",

author = "Marian Carlson and Laurent, \{Brehon C.\}",

year = "1994",

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AU - Laurent, Brehon C.

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AB - The yeast SNF/SWI proteins have a global role in transcriptional activation. This set of five proteins assists many gene-specific activators, most likely by altering chromatin structure to relieve repression. Recent work shows that the SNF/SWI proteins function together in a multiprotein complex and that SNF2 has DNA-dependent ATPase activity. SNF/SWI homologs have now been identified in Drosophila, mice and humans, suggesting a conserved role in transcriptional activation.

UR - https://www.scopus.com/pages/publications/0028292448

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DO - 10.1016/0955-0674(94)90032-9

M3 - Article

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AN - SCOPUS:0028292448

SN - 0955-0674

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EP - 402

JO - Current Opinion in Cell Biology

JF - Current Opinion in Cell Biology

IS - 3

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The SNF/SWI family of global transcriptional activators

Abstract

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